The contributions of the genome project to the study of schistosomiasis,” Memorias do Instituto Oswaldo

In this paper we review the impact that the availability of the Schistosoma mansoni genome sequence and anno-tation has had on schistosomiasis research. Easy access to the genomic information is important and several types of data are currently being integrated, such as proteomics, microarray and polymorphic loci. Access to the genome annotation and powerful means of extracting information are major resources to the research community. Key words: Schistosoma mansoni- genome- database- data integration Genome sequencing technologies have consider-ably expanded our range of tools for experimental and theoretical approaches in the quest for understanding the molecular aspects of schistosomiasis and the design of new control tools. The Schistosoma mansoni genome sequence con-tains over 360 million base pairs divided into seven pairs of autosomes and one pair of sex chromosomes (female = ZW, male = ZZ) (Berriman et al. 2009). The Wellcome Trust Sanger Institute and an inter